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Frost will hurt weed just like any other plant. As long as plastic is over though it will be alright if temps are over freezing in the day in your area. Mid april is the last frost day for the northern part of the nation.
Actually, young plants and seedlings are more resistant to frost than mature ones. For example, I had a outdoor shed grow room one year that got broke into through the window in the middle of the winter. The robber only stole a few things and left all my veging plants. The freezing cold air that came in killed all my adult plants but my starts and under a month plants were unharmed.
Yep, the younger stuff was as close as the mature stuff. Young plants are engineered to survive cold snaps as many time seedlings naturally germinate in the early spring before last frosts when temps get up in the 40-50's in the day. Ed Rosenthal has commented on this.