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 FRACTALife
Rust Fuckin' Cohle
 
Registered: 03/19/10
Posts: 6,838
Loc: Carcosa 
Last seen: 7 years, 10 months
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 drugs and our brain 
#492864 - 10/28/10 02:42 PM (14 years, 2 months ago) |
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So I was reading "What The Bleep Do We Know?" and was on the chapter about addiction. I was a little bit P.O'd about some of the stuff they said about drugs, but parts of the chapter where good and talked about emotion addiction.
Well, anyway- in one part it talked about how heroin addicts produce a lot less endogenous endorphins. I knew this, but then they went on and basically said that it is the same for all drugs, that every drug has an endogenous equal. For a second I was thinking- wait... I wonder if people who smoke lots of weed produce less endogenous cannabinoids. Then my brain turned on I realized that's bullshit. We don't produce endogenous LSD, we produce serotonin and LSD attaches to the serotonin molecule. With cannabinoids and opiates they have similar chemicals but not all drugs have equals they just have receptors. We all have certain receptors that act certain ways but the brain and drugs are complex systems. Well anyways I was just wondering what your thoughts are on all that and if you have any interesting information.
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Tangerines
Grease Wizard
Registered: 04/20/08
Posts: 9,497
Last seen: 6 years, 6 months
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 Re: drugs and our brain [Re: FRACTALife]
#492868 - 10/28/10 02:56 PM (14 years, 2 months ago) |
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LSD does not "attach" to the serotonin molecule. It simply gets accepted into the same receptors that serotonin does.
And yes if you body gets used to external products creating certain chemicals in the brain, then your brain will stop/slow production of said chemicals naturally.
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Fisherman
Stranger
Registered: 08/15/10
Posts: 940
Last seen: 10 years, 5 months
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Re: drugs and our brain [Re: Tangerines]
#492873 - 10/28/10 03:31 PM (14 years, 2 months ago) |
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Not everything is as it seems.
I believe lsd is a sacrament which can open up to other dimensions and other awesome stuff, this is not produced by a thing such as chemicals in your brain.
Silence speaks in many codes.
(also I hate arguing for some reason, but here I am.)
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Tangerines
Grease Wizard
Registered: 04/20/08
Posts: 9,497
Last seen: 6 years, 6 months
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Re: drugs and our brain [Re: Fisherman]
#492876 - 10/28/10 03:37 PM (14 years, 2 months ago) |
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Yea my dick is a sacrament too so suck it and open up dimensions and shit.
Edited by Tangerines (10/28/10 03:43 PM)
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THEBats
The Bridge Master
Registered: 04/20/08
Posts: 8,488
Last seen: 11 years, 6 months
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Re: drugs and our brain [Re: Tangerines]
#492880 - 10/28/10 04:22 PM (14 years, 2 months ago) |
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Pseudo science aside, not every drug uses this action on the brain where it has a specific site of receptors. As tangs pointed out lsd does not have a specific chemical dedicated to it but rather takes advantage of it's specific use of the serotonin pathway. Marijuana on the other hand makes use of the neurotransmitter, among others such as dopamine, but at an indirect level, mimicking the endogenous cannabinoid anandamide.
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kickin-two-hundo said:
you know what i did in english class? I came to class stoned out of my mind every day, i chugged vodka in the back of class, i put dead fish in the ceiling tiles. i put a gallon of old milk and orange juice in the file cabinet before winter vacation. i brought snakes in a tied up sweater and let them loose during class. i didnt go to school to learn, i went because i had to. i didnt care, and i didn't fucking listen to that stupid bitch. and i still don't fucking care. i tore the pages out of her books and burned them, and threw away all the books in the class, two books per day. 
Edited by THEBats (10/28/10 04:24 PM)
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Tangerines
Grease Wizard
Registered: 04/20/08
Posts: 9,497
Last seen: 6 years, 6 months
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Re: drugs and our brain [Re: THEBats]
#492882 - 10/28/10 04:24 PM (14 years, 2 months ago) |
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Is there any research between habitual marijuana use and a decline in naturally produced anandamide?
I am searching google scholar but I cannot find much specifically...maybe if I search more. I forget how to sign in and access my school databases.
But heavy marijuana use does lead to decreased dopamine activity after stopping. Not irreversible though.
http://www.pnas.org/content/95/17/10269.full
Edited by Tangerines (10/28/10 04:34 PM)
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THEBats
The Bridge Master
Registered: 04/20/08
Posts: 8,488
Last seen: 11 years, 6 months
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Re: drugs and our brain [Re: Tangerines]
#492884 - 10/28/10 04:32 PM (14 years, 2 months ago) |
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Yeah, not that I know of.
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kickin-two-hundo said:
you know what i did in english class? I came to class stoned out of my mind every day, i chugged vodka in the back of class, i put dead fish in the ceiling tiles. i put a gallon of old milk and orange juice in the file cabinet before winter vacation. i brought snakes in a tied up sweater and let them loose during class. i didnt go to school to learn, i went because i had to. i didnt care, and i didn't fucking listen to that stupid bitch. and i still don't fucking care. i tore the pages out of her books and burned them, and threw away all the books in the class, two books per day.
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 Shr0000ooooms
Cannabis Sampler
Registered: 10/22/09
Posts: 3,870
Loc: Hindu Kush Mountains
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Re: drugs and our brain [Re: Fisherman]
#492885 - 10/28/10 04:36 PM (14 years, 2 months ago) |
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Quote:
Fisherman said:
Not everything is as it seems.
I believe lsd is a sacrament which can open up to other dimensions and other awesome stuff, this is not produced by a thing such as chemicals in your brain.
Yeah, bro I feel you, because adderal gets me fucked up I feel as if it's a portal to another dimension.
Shit's tight man, zoloft does the same for me, such as caffeine and shit brah.
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If I'm posting I'm high.
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Fisherman
Stranger
Registered: 08/15/10
Posts: 940
Last seen: 10 years, 5 months
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Re: drugs and our brain [Re: Tangerines]
#492892 - 10/28/10 04:56 PM (14 years, 2 months ago) |
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Quote:
Tangerines said:
Yea my dick is a sacrament too so suck it and open up dimensions and shit.
need moar intelligent post to come up with something to saaaaay.
And shroooms, I feel you too ;D
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THEBats
The Bridge Master
Registered: 04/20/08
Posts: 8,488
Last seen: 11 years, 6 months
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Re: drugs and our brain [Re: Fisherman]
#492896 - 10/28/10 04:59 PM (14 years, 2 months ago) |
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kickin-two-hundo said:
you know what i did in english class? I came to class stoned out of my mind every day, i chugged vodka in the back of class, i put dead fish in the ceiling tiles. i put a gallon of old milk and orange juice in the file cabinet before winter vacation. i brought snakes in a tied up sweater and let them loose during class. i didnt go to school to learn, i went because i had to. i didnt care, and i didn't fucking listen to that stupid bitch. and i still don't fucking care. i tore the pages out of her books and burned them, and threw away all the books in the class, two books per day.
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King Koopa
Natty
Registered: 06/25/08
Posts: 12,819
Last seen: 2 months, 12 days
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Re: drugs and our brain [Re: THEBats]
#492956 - 10/28/10 08:12 PM (14 years, 2 months ago) |
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Quote:
FRACTALife said:
So I was reading "What The Bleep Do We Know?" and was on the chapter about addiction. I was a little bit P.O'd about some of the stuff they said about drugs, but parts of the chapter where good and talked about emotion addiction.
Well, anyway- in one part it talked about how heroin addicts produce a lot less endogenous endorphins. I knew this, but then they went on and basically said that it is the same for all drugs, that every drug has an endogenous equal. For a second I was thinking- wait... I wonder if people who smoke lots of weed produce less endogenous cannabinoids. Then my brain turned on I realized that's bullshit. We don't produce endogenous LSD, we produce serotonin and LSD attaches to the serotonin molecule. With cannabinoids and opiates they have similar chemicals but not all drugs have equals they just have receptors. We all have certain receptors that act certain ways but the brain and drugs are complex systems. Well anyways I was just wondering what your thoughts are on all that and if you have any interesting information.
Quote:
THEBats said:
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Alcoholics Anonymous is a fellowship of men and women who share their experience, strength and hope with each other that they may solve their common problem and help others to recover from alcoholism.
The only requirement for membership is a desire to stop drinking. There are no dues or fees for A.A. membership; we are self-supporting through our own contributions. A.A. is not allied with any sect, denomination, politics, organization or institution; does not wish to engage in any controversy; neither endorses nor opposes any causes. Our primary purpose is to stay sober and help other alcoholics to achieve sobriety.
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volcomstoner
Just one more xanax
Registered: 03/30/09
Posts: 4,956
Loc: Gaybec
Last seen: 7 years, 1 month
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Re: drugs and our brain [Re: King Koopa]
#492973 - 10/28/10 08:38 PM (14 years, 2 months ago) |
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drugs is good for the brain
/thread
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Vas donc jouer dans le traffic
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DieselB
High Watt Closet
Registered: 02/10/10
Posts: 1,156
Last seen: 9 years, 9 months
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Re: drugs and our brain [Re: volcomstoner]
#492985 - 10/28/10 08:54 PM (14 years, 2 months ago) |
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Have you even done banadine? It opens the mind like nothing else! you just gotta get some banana peels and.... Nevermind, this shit is too deep for most of you.
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If you ain't smokin' dro, you're smokin' reggie. 
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Inverted
CNC Machinist/Greenthumb
Registered: 06/01/08
Posts: 9,953
Loc: North Star
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Re: drugs and our brain [Re: DieselB]
#492997 - 10/28/10 09:21 PM (14 years, 2 months ago) |
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Dude, banandine has nothing on Fermented Big Red inside and Orange...
That's the digital dankles trip right there... 
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Don't criticize what you can't understand
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FurrowedBrow
Free yourself from yourself
Registered: 04/20/08
Posts: 12,045
Loc: Carpal Tunnel
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Re: drugs and our brain [Re: volcomstoner]
#493006 - 10/28/10 09:32 PM (14 years, 2 months ago) |
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Quote:
volcomstoner said:
drugs is good for the brain
/thread
that's just what they want you to think. 
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God
Yahweh
Registered: 09/26/08
Posts: 434
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Re: drugs and our brain [Re: Inverted]
#493044 - 10/28/10 11:27 PM (14 years, 2 months ago) |
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Quote:
Inverted said:
Dude, banandine has nothing on Fermented Big Red inside and Orange...
Don't forget about 
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