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Quote: FurrowedBrow said: Never mix wine and Ketamine. The firs time I did ketamine i had had a single glass of red wine and then railed a line. I felt a good initial rush, then relaxation into my body....and then sickness. I got real sick and started throwing up. I felt like i had drank 12 beers in an hour. I was hugging the toilet with a friend of mine holding my hair back. nothing too crazy, but I think it's the only drug combination i've done and wouldnt do again.