Home | Community | Message Board


High Mountain Gold Compost
Please support our sponsors.


Welcome to the Growery Message Board! You are experiencing a small sample of what the site has to offer. Please login or register to post messages and view our exclusive members-only content. You'll gain access to additional forums, file attachments, board customizations, encrypted private messages, and much more!

Shop: North Spore Injection Grain Bag   Original Sensible Seeds Bulk Cannabis Seeds   Unfolding Nature Unfolding Nature: Being in the Implicate Order   Bridgetown Botanicals CBD Capsules

Jump to first unread post Pages: < Back | 1 | 2  [ show all ]
OfflinePsilyguy


Registered: 06/15/09
Posts: 11
Last seen: 11 years, 8 months
Re: is this even possible? [Re: Harry_Ba11sach]
    #343878 - 01/09/10 03:36 AM (14 years, 11 months ago)

i dont believe its possible, but people have told me its happened to them. i would believe if i saw some evidence supporting it, but even LSD has been proven that its at least very very hard for it to happen even though everyone thinks it does.


--------------------
"Life is not a journey to the grave with the intention of arriving safely in one pretty and well preserved piece, but to skid across the line broadside, thoroughly used up, worn out, shouting GERONIMO!" -Hunter S. Thompson's version of this common quote that no one seems to know who said first...

Extras: Filter Print Post Top
InvisibleFurrowedBrowM
Free yourself from yourself
Male User Gallery


Registered: 04/20/08
Posts: 12,045
Loc: Carpal Tunnel
Re: is this even possible? [Re: Psilyguy]
    #343996 - 01/09/10 11:23 AM (14 years, 11 months ago)

it's my understanding that the good doctor first discovered the mind altering properties of lsd by accident when it was absorbed through his skin.  maybe im misunderstanding your words there, but i thought lsd was one substance that is very very easily absorbed by our skin.  I was watching bear the other night on man vs nature and he was drifting on a raft in the ocean and he gave himself an aenima with all sorts of nasty shit in it so that his body (colon) would absorb the water, becuase drinking it would have produced a terrible gag reflex.


--------------------





Multidisciplinary Association for Psychedelic Studies - Become a member!
The Growery's Herb Museum (post #24)
I prefer dangerous freedom to peaceful slavery.
~ Thomas Jefferson ~

Extras: Filter Print Post Top
OfflineNobodyImportant
Science Is Subculture
Male User Gallery


Registered: 05/03/08
Posts: 4,981
Loc: Jawjuh.
Last seen: 11 years, 7 months
Re: is this even possible? [Re: Psilyguy]
    #344003 - 01/09/10 11:28 AM (14 years, 11 months ago)

Quote:

Psilyguy said:
i dont believe its possible, but people have told me its happened to them. i would believe if i saw some evidence supporting it, but even LSD has been proven that its at least very very hard for it to happen even though everyone thinks it does.





dude you could hold doses tightly in the palm of your hand for a few minutes and I guarantee you would trip

and if its liquid, theres no question


--------------------
:bonghit:
Glass By: US Tubes, ZOB, Roor.de, Sheldon Black, Jerome Baker, Medicali, Kennaroo, Sand, Alex K, Local and Unknown Artists

Extras: Filter Print Post Top
InvisibleGod
Yahweh

Registered: 09/26/08
Posts: 434
Re: is this even possible? [Re: NobodyImportant]
    #344164 - 01/09/10 05:18 PM (14 years, 11 months ago)

Quote:

From here:

Substances that are applied to the skin can be systemically absorbed to an unknown extent. However, there have not yet been any quantitative studies of the dermal absorption of THC that would allow quantification. Nevertheless, this question is vital for the use of THC-containing products that are externally applied (cosmetics, dermatics for the treatment of neurodermitis). The physico-chemical characteristics of THC, however, allow a rough estimation of the amount of THC assimilated (Kalbitz et al. 1996, 1997).

Generally, the human skin is well protected against penetration by external substances. Many topically applied substances attain a systemic bioavailability of only a few percent (Hadgraft 1996). The main barrier to penetration is the cornea (stratum corneum), or more accurately, the cornified layer of the stratum corneum. In principle, substances can penetrate the space between the cells of the stratum corneum (intercellular), the cells themselves (intracellular), or the sebaceous and perspiratory glands and hair follicles. Only the first pathways of penetration generally play a relevant role (Hadgraft 1996, Kalbitz et al. 1996, Berti et al. 1995). For example, the route through the hair follicles and glands is of importance for polar molecules only. As a lipophilic molecule, THC does not belong to that group.

The permeation coefficient or, respectively, the permeability constant (Kp) constitute a quantitative expression for the ability of a substance to permeate the skin. The flux or absorption rate of a chemical results from a multiplication of the concentration (C) of a chemical on the skin surface with the permeability constant: flux = KpC (Mattie et al. 1994). The basic principles of absorption through the skin correspond to those of diffusion through semi-permeable membranes (Berti et al. 1995). Factors that influence the penetration through the skin are the thickness and condition of the skin, as well as the size of the penetrating substance and the carrier.

Molecules that enter and diffuse through the skin have to penetrate a number of lipid bilayers in the intercellular space, thereby repeatedly alternating from lipophilic to hydrophilic areas. Those molecules that are sufficiently lipophilic, such as glucocorticoids, easily cross those lipophilic phases. Thus, most publications still maintain as a rule that "highly lipophilic compounds with low molecular weights demonstrate the greatest flow rate through the stratum corneum" (Berti et al. 1995).

Occasionally, a direct relation between the coefficient of permeation and the octanol/water distribution coefficient is postulated (Guy 1995). The latter is a measure of a chemical's lipophilic and hydrophilic properties, respectively. A higher coefficient indicates stronger lipophilic characteristics. However, such a correlation could not be verified in experimental studies. Mattie et al. (1994) examined 13 substances with octanol/water coefficients ranging from zero to 1,400. The constant of permeability correlated only weakly with the octanol/water distribution coefficient (r2 = 0.04).

Instead, there is evidence that only a small fraction of strongly lipophilic substances, such as THC, overcomes the hydrophilic phases of the intercellular space. Gabriele Bast (1997) carried out a large number of experiments that involved different substances of differing lipophilic characteristics in different carriers, and stated: "When substances are applied in a lipophilic carrier the permeation coefficient Kp is notably decreased when the distribution coefficient (n-octanol/perfusion buffer (pH 7.4)) Poct exceeds 2000."

Conclusion: It may validly be assumed that, with an octanol/water distribution coefficient of 6,000 (Agurell et al. 1986), i.e. a strong lipophilic tendency, only a small amount of THC permeates the skin-and is systemically absorbed only on a small scale-when administered in an oily base [my emphasis], such as in cosmetics containing hemp oil. Based on experimental evidence obtained for other chemicals with known physico-chemical properties, the transdermal systemic bioavailability of THC thus is likely considerably less than the oral systemic bioavailability. Corresponding experimental studies should be conducted that quantify the exact rate of skin permeation.




(Another link here.)

But alcohol is not an oil, and THC is alcohol soluble, so:

Quote:

From here:

Absorption of ethyl alcohol into the blood can occur through the skin and via the lungs, though the major route of taking ethyl alcohol into the body is by drinking alcoholic beverages.

Absorption through the skin has been confirmed by a report (Dalt et al, 1991) of a case of a 1 – month old infant who became intoxicated as a result of absorption of ethyl alcohol from dressings applied to the stump of the umbilical cord and the skin adjacent to it.

Additional confirmation of skin absorption comes from a microdialysis study in which a long probe with was inserted under the skin for a distance of 3 cm. Ethyl alcohol was then placed in a small area on the skin above the probe while the subcutaneous area was being perfused. Analysis of the perfusate indicated the presence in an amount that was related to the extent of skin exposure (Anderson et al, 1991).




Thoughts?

Extras: Filter Print Post Top
OfflineNobodyImportant
Science Is Subculture
Male User Gallery


Registered: 05/03/08
Posts: 4,981
Loc: Jawjuh.
Last seen: 11 years, 7 months
Re: is this even possible? [Re: NobodyImportant]
    #344798 - 01/10/10 12:34 AM (14 years, 11 months ago)

Quote:

NobodyImportant said:

there was probably a small amount of alcohol left in it that helped it absorb into your skin faster and that alcohol would have been highly saturated in THCa




--------------------
:bonghit:
Glass By: US Tubes, ZOB, Roor.de, Sheldon Black, Jerome Baker, Medicali, Kennaroo, Sand, Alex K, Local and Unknown Artists

Extras: Filter Print Post Top
InvisibleTriptonic
Male


Registered: 06/13/08
Posts: 15,581
Loc: Flag
Re: is this even possible? [Re: NobodyImportant]
    #344799 - 01/10/10 12:35 AM (14 years, 11 months ago)

Quote:

NobodyImportant said:
Quote:

NobodyImportant said:

there was probably a small amount of alcohol left in it that helped it absorb into your skin faster and that alcohol would have been highly saturated in THCa






Extras: Filter Print Post Top
Invisibledeladude
king size
Male


Registered: 09/07/09
Posts: 133
Re: is this even possible? [Re: Triptonic]
    #344819 - 01/10/10 01:03 AM (14 years, 11 months ago)

hahaha. it happens to me all the time when i harvest sclerotia. i always wipem off n cut em up for drying. 3/4 the way through when my hands are soked im like "wow im feeling a bit light headed maybe you should drive".

Extras: Filter Print Post Top
OfflineNobodyImportant
Science Is Subculture
Male User Gallery


Registered: 05/03/08
Posts: 4,981
Loc: Jawjuh.
Last seen: 11 years, 7 months
Re: is this even possible? [Re: deladude]
    #344845 - 01/10/10 02:23 AM (14 years, 11 months ago)

harvest sclerotia



explain ?

google was no help to me :shrug:


--------------------
:bonghit:
Glass By: US Tubes, ZOB, Roor.de, Sheldon Black, Jerome Baker, Medicali, Kennaroo, Sand, Alex K, Local and Unknown Artists

Extras: Filter Print Post Top
Invisibledeladude
king size
Male


Registered: 09/07/09
Posts: 133
Re: is this even possible? [Re: NobodyImportant]
    #344847 - 01/10/10 02:28 AM (14 years, 11 months ago)

atl #7
boomers dude! lol
the kind that grow under ground:shrug::tongue:

Extras: Filter Print Post Top
OfflineHarlz


Registered: 02/05/09
Posts: 4,449
Loc: cloudz
Last seen: 10 months, 25 days
Re: is this even possible? [Re: deladude]
    #344894 - 01/10/10 10:18 AM (14 years, 11 months ago)

they are like nuts that grow in grain jars double the potency fresh and super stealth

Extras: Filter Print Post Top
OfflineI_AM_SWIM
Someone Who Isn't McKenna


Registered: 06/08/09
Posts: 1,337
Last seen: 12 years, 5 months
Re: is this even possible? [Re: Harlz]
    #345085 - 01/10/10 04:08 PM (14 years, 10 months ago)

anythang is possible


just like how some thangs are impossible


because of the possibility of some thangs bein impossible


draw a square circle, easy


if u draw a square with a bunch of lines, then u can draw a circle with a bunch of lines

lines = lines

which = doin' thangs

doin' thangs = possibilities.


doin' possible thangs impossibly while doin' them thangs possibly, AND feelin'g good man simultaneously , =  :feelsgoodman:


--------------------
:tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna::tmckenna:

Extras: Filter Print Post Top
Invisibledeladude
king size
Male


Registered: 09/07/09
Posts: 133
Re: is this even possible? [Re: I_AM_SWIM]
    #345096 - 01/10/10 04:16 PM (14 years, 10 months ago)

the absince of evidence isn't the evidence of absince

Extras: Filter Print Post Top
OfflineHarlz


Registered: 02/05/09
Posts: 4,449
Loc: cloudz
Last seen: 10 months, 25 days
Re: is this even possible? [Re: deladude]
    #345100 - 01/10/10 04:19 PM (14 years, 10 months ago)

Quote:

deladude said:
the absince of evidence isn't the evidence of absince



i posted that like a week ago, and spelled it right:grrr:

but it:feelsgoodman: to be doin thangs and seein swim doin thangs too

Extras: Filter Print Post Top
Jump to top Pages: < Back | 1 | 2  [ show all ]

Shop: North Spore Injection Grain Bag   Original Sensible Seeds Bulk Cannabis Seeds   Unfolding Nature Unfolding Nature: Being in the Implicate Order   Bridgetown Botanicals CBD Capsules


Similar ThreadsPosterViewsRepliesLast post
* Making Hash Oil Tonight KaptKid 1,366 9 07/15/12 12:04 AM
by KaptKid
* Can you plug marijuana/hash? What about Salvia Divinorum?
( 1 2 all )
kidaihuan 13,723 31 06/19/08 08:35 AM
by kidaihuan
* sound absorbency: are NRCs all you need? God 1,056 2 11/09/09 03:13 PM
by God
* Methods of Ingesting Hash and Charas (Kief) nick-onelove 12,917 19 07/02/11 10:10 PM
by chowdan
* Would keeping cannabis in plastic coffee container absorb thc or ruin weed? Mr.Hybrid 1,449 4 10/25/12 01:44 PM
by RasJeph
* Anyone try making hash like this? RasJeph 3,369 13 01/14/11 12:33 PM
by RasJeph
* Which skin do you use for the Growery + Shroomery
( 1 2 all )
Inverted 7,474 20 11/06/09 04:55 PM
by Triptonic
* whats you skin? 42047 3,054 18 10/03/09 12:07 PM
by MFDoom666

Extra information
You cannot start new topics / You cannot reply to topics
HTML is disabled / BBCode is enabled
Moderator: FurrowedBrow, Harry_Ba11sach, Magash, Data, Stoneth, Dr. Siekadellyk
7,045 topic views. 2 members, 325 guests and 531 web crawlers are browsing this forum.
[ Show Images Only | Sort by Score | Print Topic ]
Search this thread:
Original Seeds Store
Please support our sponsors.

Copyright 1997-2024 Mind Media. Some rights reserved.

Generated in 0.026 seconds spending 0.005 seconds on 13 queries.