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                            SUBSTANCE IDENTIFICATION
                                                    CAS NUMBER: 1972-08-3
                                                    RTECS NUMBER: HP8225000
SUBSTANCE: TETRAHYDROCANNABINOL
TRADE NAMES/SYNONYMS:
  6H-DIBENZO(B,D)PYRAN-1-OL, 6A,7,8,10A-TETRAHYDRO-6,6,9-TRIMETHYL-3-
  PENTYL-, (6A(R)-TRANS)-;
  (6A(R)-TRANS)-6A,7,8,10A-TETRAHYDRO-6,6,9-TRIMETHYL-3-PENTYL-6H-
  DIBENZO(B,D)PYRAN-1-OL;
  CANNABINOL, DELTA-1-TETRAHYDRO-; (L)-DELTA-1-TETRAHYDROCANNABINOL;
  TRANS-DELTA-9-TETRAHYDROCANNABINOL; DELTA-1-TETRAHYDROCANNABINOL;
  DELTA-9-TETRAHYDROCANNABINOL; THC; DELTA-1-THC; DELTA-9-THC; C21H30O2;
  OHS23005
CHEMICAL FAMILY:
POLYCYCLIC, HETERO
MOLECULAR FORMULA: C21-H30-O2
MOLECULAR WEIGHT: 314.45
CERCLA RATINGS (SCALE 0-3):  HEALTH=3  FIRE=1  REACTIVITY=0  PERSISTENCE=1
NFPA RATINGS (SCALE 0-4):  HEALTH=3  FIRE=1  REACTIVITY=0
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                          COMPONENTS AND CONTAMINANTS
COMPONENT: TETRAHYDROCANNABINOL                            PERCENT: 100.0
            CAS# 1972-08-3
OTHER CONTAMINANTS: NONE
EXPOSURE LIMITS:
  NO OCCUPATIONAL EXPOSURE LIMITS ESTABLISHED BY OSHA, ACGIH, OR NIOSH.
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                                  PHYSICAL DATA
DESCRIPTION: SOLID.    BOILING POINT: 392 F (200 C) @ 0.02 MMHG
MELTING POINT: NOT AVAILABLE    SPECIFIC GRAVITY: NOT AVAILABLE
SOLUBILITY IN WATER: NOT AVAILABLE
SOLVENT SOLUBILITY: SOLUBLE IN ETHANOL.
1                                                  OHS23005    PAGE 002 OF 006
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cubie said:

lol @ SOLUBLE IN ETHANOL. I hear chloroform is so much better.

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  HEALTH EFFECTS AND FIRST AID

INHALATION:
TETRAHYDROCANNABINOL:
NARCOTIC.

  ACUTE EXPOSURE-
SINCE TETRAHYDROCANNABINOL IS AN ACTIVE INGREDIENT IN
    MARIJUANA, THE TOXIC EFFECTS WILL BE SIMILAR TO THOSE OF MARIJUANA.
    INHALATION OF MARIJUANA SMOKE MAY IRRITATE MUCOUS MEMBRANES CAUSING
    DRYNESS, HOARSENESS AND BRONCHODILATION. RHINITIS, PHARYNGITIS AND ASTHMA
    MAY ALSO OCCUR ACUTELY, BUT ARE MORE COMMON AFTER CHRONIC EXPOSURE.
    SYSTEMIC EFFECTS MAY OCCUR AS DETAILED IN ACUTE INGESTION.
 

CHRONIC EXPOSURE- SNIFFING MARIJUANA MAY CAUSE AN ULCERATED OR PERFORATED
    NASAL SEPTUM. REPEATED SMOKING MAY RESULT IN COUGH, LARYNGITIS,
    BRONCHITIS, OTHER RESPIRATORY EFFECTS AS IN ACUTE INHALATION AND
    PULMONARY FUNCTION IMPAIRMENT. LONG-TERM USE BY HUMANS AND EXPERIMENTAL
    ANIMALS HAS LEAD TO SQUAMOUS METAPLASIA OF THE TRACHEAL MUCOSA. SYSTEMIC
    EFFECTS MAY OCCUR AS DETAILED IN CHRONIC INGESTION. REGULAR CHRONIC USE
    MAY RESULT IN REPRODUCTIVE EFFECTS IN MALES INCLUDING DECREASED TESTICULAR
1                                                  OHS23005    PAGE 003 OF 006
    SIZE, TESTOSTERONE LEVELS, SPERM COUNT AND MOTILITY AND ABNORMALITIES
    IN SPERM. GYNECOMASTIA MAY DEVELOP WITH HEAVY USE. FEMALES MAY EXPERIENCE
    A HIGH FREQUENCY OF ABNORMAL PERIODS, LESS OVULATION AND DECREASED
    PROLACTIN LEVELS. REPRODUCTIVE EFFECTS HAVE ALSO BEEN REPORTED IN
    ANIMALS.


FIRST AID- REMOVE FROM EXPOSURE AREA TO FRESH AIR IMMEDIATELY. IF BREATHING
  HAS STOPPED, PERFORM ARTIFICIAL RESPIRATION. KEEP PERSON WARM AND AT REST.
  TREAT SYMPTOMATICALLY AND SUPPORTIVELY. GET MEDICAL ATTENTION IMMEDIATELY.


SKIN CONTACT:
TETRAHYDROCANNABINOL:
  ACUTE EXPOSURE- NO DATA AVAILABLE.
  CHRONIC EXPOSURE- APPLICATION OF "TAR CANNABIS" RESIDUALS TO ANIMAL SKIN
    RESULTED IN TUMOR PRODUCTION.
FIRST AID- REMOVE CONTAMINATED CLOTHING AND SHOES IMMEDIATELY. WASH AFFECTED
  AREA WITH SOAP OR MILD DETERGENT AND LARGE AMOUNTS OF WATER UNTIL NO
  EVIDENCE OF CHEMICAL REMAINS (APPROXIMATELY 15-20 MINUTES). GET MEDICAL
  ATTENTION IMMEDIATELY.


EYE CONTACT:
TETRAHYDROCANNABINOL:
  ACUTE EXPOSURE- SINCE TETRAHYDROCANNABINOL IS AN ACTIVE INGREDIENT IN
    MARIJUANA, THE TOXIC EFFECTS WILL BE SIMILAR TO THOSE OF MARIJUANA.
    SYSTEMIC ADMINISTRATION OF MARIJUANA MAY CAUSE PURPLE-YELLOW VISION,
    HYPEREMIA OF THE CONJUNCTIVA, PUPIL DILATION, SLOW REACTION TO LIGHT AND
    DIPLOPIA.
 

CHRONIC EXPOSURE- NO DATA AVAILABLE.
FIRST AID- WASH EYES IMMEDIATELY WITH LARGE AMOUNTS OF WATER OR NORMAL SALINE,
  OCCASIONALLY LIFTING UPPER AND LOWER LIDS, UNTIL NO EVIDENCE OF CHEMICAL
  REMAINS (APPROXIMATELY 15-20 MINUTES). GET MEDICAL ATTENTION IMMEDIATELY.


INGESTION:
TETRAHYDROCANNABINOL:
NARCOTIC.
  ACUTE EXPOSURE- SINCE TETRAHYCROCANNABINOL IS AN ACTIVE INGREDIENT IN
    MARIJUANA, THE TOXIC EFFECTS WILL BE SIMILAR TO THOSE OF MARIJUANA.
    INGESTION OF LOW TO MODERATE AMOUNTS OF MARIJUANA MAY CAUSE RELAXATION,
    EUPHORIA, AN ALTERED TIME AND SPACE PERCEPTION, VIVID OLFACTORY, AUDITORY
    AND VISUAL SENSES, DISORIENTATION, AND SLEEP, VISUAL AND BODY IMAGE
    DISTURBANCES. INFORMATION LEARNED WHILE INTOXICATED MAY BE POORLY
    RECALLED. DIFFICULTY WITH COGNITIVE FUNCTIONS SUCH AS SPEECH AND
    ORGANIZATION OF THOUGHTS MAY BE ASSOCIATED WITH IMPAIRED SHORT TERM
    MEMORY. PSYCHOMOTOR PERFORMANCES MAY ALSO BE IMPAIRED. OTHER EFFECTS MAY
    INCLUDE DRY MOUTH AND THROAT, HEADACHE, NAUSEA, VOMITING, WEAKNESS,
    RESTLESSNESS, TINNITUS, APPETITE STIMULATION POSSIBLY DUE TO
    HYPOGLYCEMIA, TREMOR, DELIRIUM, JOCULARITY, STUPOR, ATAXIA, DEPRESSION,
    AGGRESSIVENESS AND PARESTHESIAS. RESIDUAL SEDATION MAY PERSIST THE
    FOLLOWING DAY. POSSIBLE CARDIOVASCULAR EFFECTS INCLUDE HYPERTENSION OR
    HYPOTENSION, SINUS TACHYCARDIA AND PREMATURE VENTRICULAR CONTRACTIONS.
    LARGE DOSES MAY LEAD TO DEPERSONALIZATION, LOSS OF INSIGHT, ANXIETY,
    PARANOIA, ACUTE PSYCHOSIS AND OBSESSIONAL THOUGHT CHARACTERIZED BY
    DELUSIONS, HALLUCINATIONS, ILLUSIONS AND BIZARRE BEHAVIOR. DEATH IS RARE
    BUT MAY RESULT FROM RESPIRATORY ARREST OR CARDIOVASCULAR COLLAPSE. EFFECTS
    ON SPERMATOGENESIS IN MICE HAVE BEEN REPORTED FROM ADMINISTRATION OF A
    SINGLE DOSE.
1                                                  OHS23005    PAGE 004 OF 006
  CHRONIC EXPOSURE- REPEATED INGESTION MAY RESULT IN A LOWERING OF THE
    SENSORY THRESHOLD, APATHY, DULLNESS, ANXIETY, PANIC, AGGRESSIVENESS,
    DISORIENTATION, CONFUSION, CLOUDING OF MENTAL PROCESSES WITH IMPAIRED
    JUDGEMENT AND MEMORY, LOSS OF PERSPECTIVE, REDUCED MOTIVATION AND
    ACUTE INSECURITY. WEIGHT GAIN MAY OCCUR DUE TO APPETITE STIMULATION.
    FLASHBACKS HAVE BEEN REPORTED. REDUCED T-LYMPHOCYTES AND IMPAIRED
    CELL-MEDIATED IMMUNITY MAY OCCUR. TOLERANCE AND PSYCHOLOGICAL AND PHYSICAL
    DEPENDENCE MAY DEVELOP WITH HEAVY PROLONGED USE. SYMPTOMS OF WITHDRAWAL
    MAY OCCUR. MAY BE EXCRETED IN BREAST MILK. REPRODUCTIVE EFFECTS HAVE BEEN
    REPORTED IN ANIMALS.
FIRST AID- TREAT SYMPTOMATICALLY AND SUPPORTIVELY. GET MEDICAL ATTENTION
  IMMEDIATELY. IF VOMITING OCCURS, KEEP HEAD LOWER THAN HIPS TO PREVENT
  ASPIRATION.
ANTIDOTE:
NO SPECIFIC ANTIDOTE. TREAT SYMPTOMATICALLY AND SUPPORTIVELY.

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