Different types of high associated with Indica, Sativa and hybrid strains.
Different strains have different highs.
Generally speaking...
Indica plants offer a heavy, stony high that is relaxing and can help different medical problems. Often referred to as the "couch lock" high.
Sativa plants have an energetic, somewhat more psychedelic high which can stimulate brain activity and may produce hallucinations. Often referred to as a "cerebral" high.
Hybrid strains have a combination of both Indica and Sativa highs which are relative to strain ratio.